Whilst, higher levels of IL-8 have positively correlated with weight loss and sarcopenia in pancreatic cancer [percentage weight loss to define cachexia (> 5%) and computed tomography (CT) images for the diagnosis of sarcopenia] (Hou et al. 2018), the current study found that IL-8 was only significantly related with CSS categories, but not with sarcopenia, HGS, or protein status, potentially explained by differences in cachexia and sarcopenia definitions employed. The gene discussed is CXCL8; the disease is familial pancreatic carcinoma.