Combined with the clinical data from TCGA-stomach adenocarcinomas (STAD) cohort, univariate Cox analysis demonstrated that THSD7A expression [hazard ratio (HR) = 1.741, 95% confidence interval (CI): 1.165–2.601, P = 0.007], age (HR = 1.024, CI: 1.006-1.042, P = 0.010), T-stage (HR = 1.225, CI: 1.001-1.573, P = 0.049), and N-stage (HR = 1.327, 95% CI: 1.132-1.555, P < 0.001) were significantly associated with a high-risk ratio (Figure 4A). Here, THSD7A is linked to gastric adenocarcinoma.