We also found that cells with high XCL2 expression recruited more M1 macrophages using tissue immunofluorescence staining; in vitro experiments revealed that cancer cells were able to recruit more M1 macrophages after XCL2 overexpression in 786O, U251, and MDA-MB-231 cells, which was consistent with the results of our previous bioinformatics analysis. This evidence concerns the gene XCL2 and cancer.