KCNJ10 and Isaacs syndrome: Although clinical myokymia and neuromyotonia was common in dogs with spinocerebellar ataxia and biallelic for the KCNJ10 variant (21 out of 27 dogs in this study, 78%), a proportion of such dogs (6 out of 27 dogs, 22%) did not have signs of myokymia and/or neuromyotonia.