HoLEP vs. TURIS Lesser drop in Hb levels (p<0.002) Anemia necessitating blood transfusion (4 vs. 0, p=0.03) Capsular violation (5 vs. 0, p<0.01) AUR requiring recatheterization and postoperative hematuria (0 vs. 1 and 4 vs. 3 respectively) Recurrent obstructive LUTs (2 vs. 11, p=0.01) LUTs with residual prostate adenoma (0 vs. 6, p<0.04) Bladder neck contracture (1 vs.0) Persistent urge urine incontinence (6 vs. 6). The gene discussed is GSTM1; the disease is anemia (phenotype).