NLR family, pyrin domain containing 3 (NLRP3) inflammasome is a multimeric complex consisting of three parts NLRP3 receptor protein, pro‐caspase‐1, and apoptosis speck‐like protein and is implicated in airway inflammation in both COPD and asthma.5 The gene discussed is NLRP3; the disease is chronic obstructive pulmonary disease.