Compared with H. pylori‐negative pSS group, patients with H. pylori‐positive pSS group displayed a lower hematocrit (median g/L, 42.95 vs. 41.19, p = .013), glutamic‐pyruvic transaminase (GPT) (median U/L, 16 vs. 8, p = .017), ALP (median U/L, 64 vs. 77, p = .002) and γ‐glutamyl transpeptidase (γ‐GT, median U/L, 18 vs. 25.5, p = .001). The gene discussed is GPT; the disease is peeling skin syndrome.