To explore the specific mechanism of TNIP2 in the course of endometritis in this study, hEECs were pretransfected with a control‐plasmid/TNIP2‐plasmid or treated with NF‐κB agonist CU‐T12‐9 for 24 h and then treated with 1 μg/mL LPS for 3 h. This evidence concerns the gene TNIP2 and endometritis.