Based on the capability of hormone secretion, PA is sorted into NFPA and FPA; the latter further includes growth hormone (GH) adenoma, prolactin (PRL)‐secreting adenomas (also known as prolactinoma), adrenocorticotropic hormone (ACTH) adenoma, thyroid‐stimulating hormone (TSH) adenoma, luteinizing hormone (LH) adenoma, and follicle‐stimulating hormone (FSH) adenoma (see Figure 1).18 This evidence concerns the gene POMC and adenoma.