The results showed that patients with osteomyelitis had increased expression of CXCL10, CXCL13, CXCR2, FCGR3B, IL1B, IL8, MMP9, and S100A12 and decreased expression of CXCL9, LCN2, MMP1, and MMP3 compared to normal subjects (Fig. 5). The gene discussed is IL1B; the disease is osteomyelitis.