It mainly recruits and activates a variety of cells expressing CXC chemokine receptor 1 and 2, participates in the regulation of cell migration, invasion and angiogenesis.[35] At present, the research on CXCL3 mainly focuses on tumor immunity.[36] Blocking CXCL3 signal transduction pathway can inhibit the pathophysiological processes such as cell migration, invasion, angiogenesis, tumorigenesis and fibrosis, which may become a potential prevention and treatment target for a variety of diseases. This evidence concerns the gene CXCL3 and neoplasm.