Important regulators of cancer and development are noncoding RNAs.[52] Through controlling HIF-1α, several of these noncoding RNAs can support biological functions associated with tumors, including cell survival, tumor spread, immunological evasion, and metabolic reprogramming.[53–55] In recent years, noncoding RNAs which regulate HIF-1α have been extensively investigated; but their exploration in TNBC is restricted, and some of the mechanisms are yet unclear. This evidence concerns the gene HIF1A and neoplasm.