The tumor microenvironment, especially the immune aspect, profoundly impacts cancer outcomes and immune evasion.[31] In our study, we constructed a gene-gene functional interaction network and identified a number of KIF genes that could interact with KIFC2 including KIF6, KIF27, KIF19, KIF12, KIF25, KIF18B, KIF7, KIF2B, KIF17, KIF20A, KIF5C, and KIF4A. This evidence concerns the gene KIF18B and cancer.