The immune cells composition in the tumor environment significantly influences prognosis and therapy response.[37] Different lymphocyte types can both help and hinder disease progression.[38,39] Some recent colon cancer therapies failed due to low immune cell infiltration.[40] Our data emphasize the association between identified kinesins and CD4 + and CD8 + T cells, key in antitumor responses. The gene discussed is CD8A; the disease is malignant colon neoplasm.