However, aspirin has been shown to promote anoikis and inhibit breast cancer metastasis through COX inactivation and to decrease TAX2 by generating anoikis resistance through sustained Akt activation and subsequent stimulation of breast cancer metastasis to the lung.[13] Despite these findings, there has been limited exploration of breast cancer prognostic models based on anoikis-related genes (ANRGs). Here, AKT1 is linked to breast cancer.