This study showed that the mean values of albumin and total protein were not statistically significantly correlated with the severity of pre-eclampsia, which is not consistent with the previous study by M. Gojnic et al. [13], in which they found that all patients with severe PE had values below 3.0 gm/dl, which may serve as an indicator of the severity of PE, and they propose that hypoalbuminemia in pre-eclampsia is the result of reduced hepatic blood flow secondary to hypovolemia caused by higher infiltration pressure in the capillaries. This evidence concerns the gene ALB and Hypoalbuminemia.