FLT3 and acute myeloid leukemia: For example, all five patients with FLT3 missense driver mutations in the pediatric TARGET-AML cohort belong to the ATP1A1/BCL2L1high group (Supplementary Table S9); the rare adult TCGA AML patients with KMT2A rearrangements preferentially were also ATP1A1/BCL2L1high (Supplementary Table S5).