We next aimed to compare imetelstat responses to those obtained with standard induction chemotherapy (cytarabine plus anthracycline) in AML PDX from 20 individual samples from patients with AML in an independent cohort using NOD.Rag1−/−Il2Rg−/−/ hIL3,CSF2,KITLG (NRGS) recipients14. The gene discussed is KITLG; the disease is acute myeloid leukemia.