CTTN and breast adenocarcinoma: Accordingly, 60 min after plating MDA-MB-231 breast adenocarcinoma cells on the fibrillar network, invadosomes were detected as F-actin-, cortactin- and TKS5-enriched curvilinear structures that formed at contact sites between the PM and the underlying collagen fibrils14,41,42 (Fig. 1a and Extended Data Fig. 1a).