The mediators CCL3, CCL4, CCL2, CCL5, IL-12, IL-15, IL-1Ra, and PDGF were higher in healthy volunteers, while the mediators CCL11, CXCL10, IL-1b, IL-6, TNF-a, IFN-g, IL-17, IL-9, IL-10, IL-13, FGF-basic, G-CSF, GM-CSF, IL-7, and IL-2 were increased in COVID-19 positive patients (Fig. 4). This evidence concerns the gene CSF2 and COVID-19.