Recently, several urinary new biomarkers of kidney injury, such as urinary liver-type fatty acid binding protein (L-FABP), [tissue inhibitor of metalloproteinases-2] × [insulin-like growth factor-binding protein 7] ([TIMP-2] × [IGFBP7]), or clusterin, have been noticed for early diagnosis of AKI. The gene discussed is CLU; the disease is acute kidney injury.