On the contrary, although higher levels of urinary [TIMP-2] × [IGFBP7] after TAVI in addition to those before TAVI were associated with AKI onset, our study did not show a significant difference in urinary [TIMP-2] × [IGFBP7] levels between the AKI and non-AKI groups at the early phase after TAVI. The gene discussed is IGFBP7; the disease is acute kidney injury.