Overall, the arthritis in both the whole-body Zfp36-KO mice and the M-triple KO mice is similar to the pathology observed in human rheumatoid arthritis (Komatsu & Takayanagi, 2022) and in mouse models of rheumatoid arthritis, such as collagen antibody-induced arthritis (Caplazi et al, 2015). Here, ZFP36 is linked to rheumatoid arthritis.