Interestingly, high-level copy gain (CN = 6) of both DAXX (6p21.3) and FGFR3 (4p16.3) and low-level copy gain (CN = 3) of FLNC (7q32.1) were observed in the HCC component (Supplemental Table S1). Here, FLNC is linked to hepatocellular carcinoma.