A CTNNB1 c.14-10_241+25del (p.A5_A80del) variant at a variant allele fraction (VAF) of 26%, and a c.364_368dup, p.Glu124TrpfsTer2 frameshift (p.E124fs) variant of the RPS6KA3 gene at a VAF of 67.5% were detected in the HCC-like component (Figure 2(c) and (d)). The gene discussed is RPS6KA3; the disease is hepatocellular carcinoma.