To investigate this, three extracellular and threeintracellular epitopes of epidermal growth factor receptor (EGFR)were used as templates for the synthesis of nanoMIPs which were thenused to treat cancer cells with different expression levels of EGFR.It was observed that nanoMIPs imprinted with epitopes from the intracellularkinase domain and the extracellular ligand binding domain of EGFRcaused cells to form large foci of EGFR sequestered away from thecell surface, caused a reduction in autophosphorylation, and demonstratedeffects on cell viability. The gene discussed is EGFR; the disease is cancer.