Moving forward, we plan to expand our research to encompass other miRNAs and target genes, delve deeper into the roles of other m6A modifying enzymes like METTL3 in mitochondrial homeostasis imbalance and NAFLD, and further elucidate the regulatory mechanism of SIDT2 in NAFLD. This evidence concerns the gene SIDT2 and metabolic dysfunction-associated steatotic liver disease.