CCL11 and renal cell carcinoma: We observed a significant causal effect of Eotaxin on the increased risk of RCC in males (Odds ratio [OR] = 2.546, 95% confidence interval [CI] = 1.617–4.010, p value = 5.496 × 10–5), but not in females (OR = 1.352, 95% CI = 0.766–2.388, p value = 0.298).