CHI3L1 and posterior cortical atrophy: Furthermore, CHI3L1 rs10399805 polymorphisms also displayed significant associations with the pathologic Gleason grade (OR = 0.637, 95% CI: 0.429–0.947, p = 0.026), T stage (OR = 0.564, 95% CI: 0.380–0.837, p = 0.004), seminal vesicle invasion (OR = 0.597, 95% CI: 0.377–0.946, p = 0.027) and perineural invasion (OR = 0.608, 95% CI: 0.381–0.970, p = 0.036) among elderly PCa patients carrying at least one polymorphic A allele (Table 6).