NOP16 and colorectal cancer: HSPC111 changes the lipid metabolism of fibroblasts by phosphorylating ATP citrate lyase, upregulates the level of acetyl CoA, increases the acetylation of H3K27 in cancer‐associated fibroblasts (CAFs), promotes the expression and secretion of C–X–C motif chemokine 5 (CXCL5), and affects the formation of the PMN and liver metastasis of colorectal cancer.53