KPNA4 and breast carcinoma: For instance, circ_0007331 stimulates colorectal cancer by regulating the high-mobility group A2 axis of miR-205-5p [13], circ-ABCB10 is linked with paclitaxel-resistance (PTX-R) in breast cancer via let-7a-5p/dual specificity phosphatase 7 (DUSP7) axis [14], and circ_ZFR also participates in PTX-resistance and NSCLC development by inducing karyopherin subunit alpha 4 (KPNA4) via miR-195-5p sponging [15].