Moreover, aberrant hypermethylation in the eight genes, including RASSF1, MGMT, DAPK1, CDH13, CDH1, RARB, KCNH5, and BVES, has been detected in 80% of NSCLC tissues and 14% of noncancerous tissues.126. The gene discussed is POPDC1; the disease is non-small cell lung carcinoma.