Furthermore, the SCRN2, MRPL10, and OSBPL7 are related to proteolysis, mitochondrial translation, and cholesterol metabolism, respectively, which play important roles in AD pathogenesis (Bishop et al., 2010; Strooper, 2010; Swerdlow, 2011; Picard and McEwen, 2014; Xue et al., 2018). This evidence concerns the gene SCRN2 and Alzheimer disease.