These include linear IgA bullous dermatosis, drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DiHS/DRESS) which can present with a wide range of skin morphologies, acute generalized exanthematous pustulosis (AGEP), generalized bullous fixed drug eruption (GBFDE), bullous lichenoid, and multiforme-like drug eruption caused by various medications, and more recently, by the immune checkpoint inhibitors and most commonly PD-1 and PDL-1 inhibitors used in lung cancer. The gene discussed is CD274; the disease is lung cancer.