On the other hand, HLA-A11, HLA-A*11:01, HLA-A23, HLA-A*31:01, HLA-B*13:01, HLA-B14, HLA-B22, HLA-B27, HLA-B55, HLA-B*55:02, and HLA-DR4 were found to be protective factors against NPC carcinogenesis (80, 81). This evidence concerns the gene HLA-B and nasopharyngeal carcinoma.