In contrast, the cytotoxic effect of OT-I cells on CT26.WT cells was very low when T2Kb cells and/or pOVA were not present (Table 1; rows 1, 2, and 8), and the cancer cell death rate was similar to that observed when CT26.WT and T2Kb cells were co-cultured without OT-I cells (Table 1; rows 6 and 7). Here, DDX53 is linked to cancer.