MMP2 and glioblastoma: The most popular drug inhibiting MMP-2 is chlorotoxin (CTX), a peptide derived from scorpion venom.183 Agarwal et al. incorporated CTX onto a morusin-loaded PLGA NP for GBM treatment.184 Combining MMP-2 inhibition through CTX with morusin, which inhibits MMP-2 and MMP-9 in hepatoma SK-Hep1 cells, produced a potent cytotoxic effect in vitro.