Other comorbidities included autoimmune hepatitis (7), hypothyroiditis (8), previously resected C-kit positive gastrointestinal stromal tumor and urothelial cell bladder cancer (8), tobacco use (9), gastroesophageal reflux disease (GERD) (9), dyslipidemia (10), history of pulmonary embolism (10), and anemia (11). This evidence concerns the gene KIT and metabolic syndrome.