Considering a P value ≤0.2 for the variables in univariate analysis, a low hazard ratio (HR) was estimated for patients harboring epithelioid MESO [HR, 0.49 (0.20–1.18)], absence of necrosis [HR, 0.47 (0.23–0.96)], nuclear grade 2 [HR, 0.56 (0.28–1.14)], low tumor PD-L1 level [HR, 68 (0.35–1.30)], low TME occupied by collagen type I [HR, 0.83 (0.64–1.07)], and absence of chemotherapy [HR, 0.23 (0.11–0.49)]. This evidence concerns the gene CD274 and neoplasm.