There is a positive effect in terms of laboratory parameters such as the decreasing number of eosinophils and level of total IgE in blood (28, 32, 119), increasing in cellular and humoral immunity, in particular, the number of T lymphocytes increases, eosinophilia decreases, level of circulating immune complexes decreases, while content of immunoglobulins class M and E stabilizes, itching reduces, and edema phenomena and hives decrease (24, 28, 33, 34, 113–119, 122). Here, IGHE is linked to Increased total eosinophil count.