CD8A and cancer: The pan-cancer analysis indicated that the expression level of ORC6 displayed an inverse correlation with the infiltration abundance of various immune cells, including Tem CD8 cells, Th1 cells, NK cells, pDCs, iDCs, eosinophils, monocytes, and neutrophils, while showing a positive correlation with the infiltration abundance of Act CD8 cells and Th2 cells (Figure 8A).