S100A12 and Sepsis: By intersecting data from WGCNA (3396 genes) and DEGs (8973 genes) with the 69 NETs-related genes, we identified 13 genes (Figure 4A): RIPK3, PADI4, ITGAM, FCAR, CYBB, SIGLEC14, S100A12, ALPL, DNASE1, G0S2, TLR7, SLC22A4, and MMP9. These 13 genes were then compared with the GSE65682 dataset, and they were found to be significant DEGs between the healthy and sepsis groups (Figures 4B–D).