The recognition of the PSMA as an appropriate target for the PCa lesions opened the opportunity for the development of an extensive array of radiopharmaceuticals intended for theranostic purposes, using targeted radionuclide therapy (TRT) and molecular imaging techniques, i.e., single photon emission computed tomography (SPECT) or positron emission tomography (PET). The gene discussed is FOLH1; the disease is posterior cortical atrophy.