Given that homologous encoding somatic mutations (i.e., BRAF p.V595E) are highly recurrent in some tumors of dogs, including papillary OSCC and urothelial carcinoma (20, 27, 38), VE1 IHC might be a useful tool that would complement RAS Q61R-specific SP174 antibody IHC. Here, P2RY13 is linked to urothelial carcinoma.