Reports on immunostaining of granulomas have enabled further characterisation of granulomas; Turner et al. (45) describe the lymphocytic population in the non-necrotic, solid granulomas, comprising of significant numbers of CD4+ cells with fewer CD8+ cells; interestingly, in contrast to mice, these cells were distributed randomly within the lesions without aggregating. The gene discussed is CD8A; the disease is Granuloma.