GLUT1 manifestation in anaerobic glycolysis and hypoxia of tissues promote tumor growth [10] and its survival; hence, GLUT expression alteration is reported in premalignancy and malignancy with altered GLUT1 responses in relation to the clinical staging and histopathological grading of OSCC as a prediction revealed based on its aggressiveness and prognosis [11,12]. This evidence concerns the gene SLC2A1 and neoplasm.