DYRK1A and cancer: Finally, DYRK1A could also modulate cancer risk by interacting with oncogenic viral proteins that target cell cycle regulators, such as Adenovirus E1A protein, high-risk HPV16/18 E7 proteins as well as cutaneous HPV E6 proteins (Liang et al., 2008; Cohen et al., 2013; Kuppuswamy et al., 2013).