Various studies have investigated the anticancer properties of quercetin and its role in preventing the growth, proliferation, and progression of cancer through different cellular signaling pathways, such as the PI3K/Akt/mTOR, nuclear factor kappa B (NF-κB), Wnt/β-catenin signalling, mitogen-activated protein kinase (MAPK), p53 signalling and Janus kinase (JAK)/signal transducer and transcription activator (STAT) signalling pathways (Khan et al., 2016; Asgharian et al., 2022). The gene discussed is PIK3CA; the disease is cancer.