SHBG and type 2 diabetes mellitus: In female patients with type 2 diabetes, sex hormone binding globulin (β: -0.154, 95%CI: -0.193, -0.116, p<0.001) decreased, but bioavailable testosterone (β: 0.077, 95%CI: 0.058, 0.096, p<0.001) showed the opposite trend (Figure 2).