Both the common effect model (HR=0.53, 95%CI [0.44-0.62], Z=-7.35, p<0.0001) and random effects model (HR=0.50, 95%CI [0.40-0.63], Z=-5.99, p<0.0001) demonstrated GATA3 as a favorable protective factor against BC recurrence. The gene discussed is GATA3; the disease is breast cancer.