Therefore, it is not difficult to understand that the M1 macrophages in the anterior orbital tissue of TAO are increased and the M2 macrophages are decreased compared with the normal subjects, and these OFGs (especially LINC01140 and LINC01697) have a negative association with M1 macrophages and a positive association with M2 macrophages to varying degrees. Here, LINC01140 is linked to thromboangiitis obliterans.