In lipid metabolism tests, in addition to lower high density lipoprotein cholesterol (HDL-C) in GDM group, parameters including total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (apo-A1), apolipoprotein B (apo-B) and small dense low density lipoprotein cholesterol (sdLDL-C) were higher in GDM group (all P < 0.05). The gene discussed is APOA1; the disease is gestational diabetes.