Although flumazenil is a positive modulator of α2βγ2 and α3βγ2 GABAA receptors [23], CGCs do not express these receptors [1], and flumazenil lacks activity for α1βγ2 receptors [23], so that the ability of this drug to suppress tremor in WT but not in α6 KO mice is consistent with an action on CGC α6βγ2 receptors. This evidence concerns the gene TWF1 and Tremor.